MONOSTOTIC OSTEOFIBROUS DYSPLASIA OF THE TIBIA

  • Maimoona Siddique Nuclear Medicine Department, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore
  • Humayun Bashir Nuclear Medicine Department, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore
  • Imran K Niazi Radiology Department, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore
  • Ahsan Shamim Surgical oncology department, Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore

Abstract

An 11-year-old boy presented with painful swelling of leg following fracture of tibia. Osteo brous dysplasia (OFD) is an uncommon, benign, non-hereditary bone disorder in which brous tissue develops in place of normal bone that affects the young adults in their rst and second decade of life. Tc-99m MDP whole-body bone scintigraphy revealed increased tracer uptake in dense proximal tibia. On single-photon remission computed tomography-computed tomography (SPECT-CT), radiological features of cortical-based lesion superimposed on abnormal tracer uptake con rmed it to be a monostotic OFD. This case emphasises the role of SPECT-CT and magnetic resonance imaging in detecting osteo brous dysplasia and differentiating it from other benign bone conditions. 

Key words: Bone scintigraphy, magnetic resonance imaging, monostotic osteo brous dysplasia, single-photon emission computed tomography computed tomography, tibia

References

McCaffrey M, Letts M, Carpenter B, et al. Osteo brous dysplasia: A review of the literature and presentation of an additional 3 cases. Am J Orthop 2003;32:479-86.

Gleason BC, Liegl-Atzwanger B, Kozakewich HP, et al. Osteo fibrous dysplasia and adamantinoma in children and adolescents: A clinicopathologic reappraisal. Am J Surg Pathol 2008;32:363-76.

Frangenheim P. Congenital ostitis brosa as the cause an intrauterine fracture of the lower leg. Arch Klin Chir 1921;117:22 9.

Campanacci M. Osteo brous dysplasia of long bones a new clinical entity. Ital J Orthop Traumatol 1976;2:221-37.

Feller L, Wood NH, Khammissa RA, et al. The nature of fibrous dysplasia. Head Face Med 2009;5:22.

Davidson D, Chapurlat G. Osteofibrous Dysplasia. Available from: http://www emedicine.medscape.com/ article/1256595-overview. [Last accessed on 2016 Mar 11].

Campanacci M, Laus M. Osteo brous dysplasia of the tibia and fibula. J Bone Joint Surg Am 1981;63:367-75.

Ishida T, Iijima T, Kikuchi F, et al. A clinicopathological and immunohistochemical study of osteo brous dysplasia, differentiated adamantinoma, and adamantinoma of long bones. Skeletal Radiol 1992;21:493-502.

Zamzam MM. Congenital osteo brous dysplasia of the tibia, associated with pseudoarthrosis of the ipsilateral bula. Saudi Med J 2008;29:1507-9.

Lee RS, Weitzel S, Eastwood DM, et al. Osteo brous dysplasia of the tibia. Is there a need for a radical surgical approach? J Bone Joint Surg 2006;88:658-64.

Bosse A, Niesert W, Wuisman P, et al. Fibrous dysplasia versus osteofibrous dysplasia. Morphological, differential diagnostic and clinical aspects. Experiences from the Westfalen bone tumor registry. Z Orthop Ihre Grenzgeb 1993;131:42-50.

DiCaprio MR, Enneking WF. Fibrous dysplasia. Pathophysiology, evaluation, and treatment. J Bone Joint Surg Am 2005;87:1848-64.

Wang K, Allen L, Fung E, et al. Bone scintigraphy in common tumors with osteolytic components. Clin Nucl Med 2005;30:655-71.

Tuncel M, Kiratli PO, Gedikoglu G. SPECT CT imaging of poliostotic brous dysplasia. Rev Esp Ned Nucl Imagen Mol 2012;31:47-8.

Nakahara T, Fujii H, Hashimoto J, et al. Use of bone SPECT in the evaluation of brous dysplasia of the skull. Clin Nucl Med 2004;29:554-9.

Published
2016-05-05
How to Cite
1.
Siddique M, Bashir H, Niazi IK, Shamim A. MONOSTOTIC OSTEOFIBROUS DYSPLASIA OF THE TIBIA. J Cancer Allied Spec [Internet]. 2016May5 [cited 2020Aug.15];2(1). Available from: https://journals.sfu.ca/jcas/index.php/jcas/article/view/57