Journal of Cancer & Allied Specialties <p>The <em>Journal of Cancer &amp; Allied Specialties </em>is a double blind peer-reviewed open access electronic journal which focuses on all aspects of <em>cancer care</em>.</p> Shaukat Khanum Memorial Trust en-US Journal of Cancer & Allied Specialties 2411-989X <p>Authors retain copyright and grant the Journal of Cancer &amp; Allied Specialties (JCAS) right-of-first publication. In addition, the work will be simultaneously licensed under a <a href="">Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license</a>. This license allows others to share the work in whole or part (for non-commercial purpose), with an acknowledgement of the work’s authorship and initial publication in JCAS.</p> <p>Furthermore, authors are free to enter into separate contractual arrangements for the non-exclusive distribution of the journal’s published version of the work, with an acknowledgement of its initial publication in this journal.</p> <p>Authors are permitted and encouraged to share their work online or in medical or scientific conferences prior to or during submission process.</p> Editorial: Cancer Registration in Pakistan, a Reality Check <p>An editorial on the current practices of cancer registration in Pakistan.&nbsp;</p> Farhana Badar Copyright (c) 2022 Farhana Badar 2022-04-17 2022-04-17 8 2 10.37029/jcas.v8i2.465 Postoperative use of abdominal binders: Bound to tradition? <p><strong>Introduction:</strong><span data-preserver-spaces="true">&nbsp;An abdominal binder is an elastic or non-elastic belt applied to the abdomen in postoperative patients with abdominal surgery. These provide support and splintage to the operative wound, reducing incision site pain. The present work aims to investigate the institutional practices regarding the use of abdominal binders, gain insight into the expected benefits that these practices are targeted to achieve, and determine if current practices are in accordance with the available evidence.&nbsp;<strong>Materials and Methods:</strong>&nbsp;It is a survey-based questionnaire study conducted at the Department of Surgical Oncology at Shaukat Khanum Memorial Cancer Hospital &amp; Research Center. Respondents were inquired about: designation, frequency of binder usage, reasons for prescribing/ not prescribing binders, duration of the prescription, clinical factors that influence the decision to use binders, and the estimated cost of the device.&nbsp;<strong>Results:</strong> The questionnaire was emailed to 85 surgeons working in the department of surgical oncology. Out of these, 34 responded, resulting in an overall response rate of 40%. 22 (64.7%) of the respondents used abdominal binders regularly in postoperative patients. 8 (22.5%) reported using it occasionally, while 4 (11.7%) did not use abdominal binders in their clinical practice. 67.8% and 50% of the respondents believed that it helped early mobilization and better pain control, respectively. About 60.7% of the respondents believed that binders prevent incisional hernia formation, while 46.4% were of the view that these prevented wound dehiscence. Up to 60% of the respondents reported using an abdominal binder for 1 week to 1 month after discharge, whereas 23.3% preferred using it only till discharge. <strong>Conclusion:</strong>&nbsp;This survey demonstrates a gap between the evidence and actual practice. These gaps are often overlooked because of busy clinical practice. Equally important is the issue of surgical conservatism and the intrinsic desire to resist change by continuing old practices.</span></p> Ibtissam Bin Khalid Mahzaib Babar Irfan Ahmed Copyright (c) 2022 Ibtissam Bin Khalid 2022-05-20 2022-05-20 8 2 10.37029/jcas.v8i2.463 Prognosis of Elderly Patients with Advanced Gastric Cancer without Serosal Invasion <p><strong>Introduction</strong>: The impact of age on the prognosis of patients with gastric cancer is controversial. This study aimed to investigate the clinicopathologic features and prognosis of elderly, advanced gastric cancer patients without serosal invasion compared to their younger counterparts. <strong>Materials and Methods</strong>: We retrospectively evaluated 43 elderly patients with advanced gastric cancer without serosal invasion. The clinicopathologic findings were compared between the elderly (age &gt;70 years) and young (age &lt;36 years) patients. <strong>Results</strong>: Significantly higher numbers of elderly patients had tumors with differentiated histology, whereas more young patients had tumors with undifferentiated histology (<em>P</em> &lt; 0.01). Curability (risk ratio, 3.122; confidence interval, 1.242-4.779; <em>P</em> &lt; 0.001) was an independent prognostic factor of survival. The 5-year survival rates were not significantly different between the elderly and the young patients according to the absence of serosal invasion (80.0% vs 77.9%; <em>P</em> = 0.654) and undergoing curative resection (82.0% vs 78.9%; <em>P</em> = 0.312). Meanwhile, among the elderly patients, those who underwent curative resection had a better survival rate than those with non-curative resection (82.0% vs 67.8%; <em>P</em> &lt; 0.001). <strong>Conclusion</strong>: Elderly patients with advanced gastric cancer without serosal invasion do not have a worse prognosis than their younger counterparts, indicating that age does not impact the prognosis of advanced gastric cancer. The important prognostic factor was whether the patients underwent curative resection.</p> Ho Gun Kim Jae Hyuk Lee Dong Yi Kim Copyright (c) 2022 Ho Gun Kim, Jae Hyuk Lee, Dong Yi Kim 2022-06-06 2022-06-06 8 2 10.37029/jcas.v8i2.467 BMI and other Risk Factors Effects on Colon Cancer Prognosis in Pakistan <p><strong>Introduction:</strong> Asian developing countries share the burden of colorectal cancer (CRC) with rising mortality rates. This prospective study aims to apprehend the clinical relevance of age, gender, lifestyle choices (dietary habits and addiction), and body mass index (BMI) to the occurrence and progression of colon cancer (CC). <strong>Methods:</strong> A cohort of non-cancer and CC patients of South-Central Asian origin registered for screening colonoscopy or surgery at Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC), Lahore, Pakistan, from 2015 - 2020 was identified. BMI (Kg/m<sup>2</sup>) was classified according to the World Health Organization (WHO) criteria as underweight (&lt;18.5 Kg/m<sup>2</sup>), normal weight (18.5-24.9 Kg/m<sup>2</sup>) and overweight (≥25 Kg/m<sup>2</sup>). <strong>Results:</strong> Among 236 participants, 99 (41.9%) belonged to the NC group, and 137 (58.1 %) participants had CC. Overall, participants included 74 women and 162 men aged 20 - 85 years (mean ± SD; 49.9 ± 14.9). Notably, 46.0 % of cancer patients had a family history of cancer. There was a direct relationship between CC with abnormal BMI (underweight and overweight), positive smoking history and positive family history of cancer. <strong>Conclusion:</strong> Being underweight or overweight is a potential risk factor for CC patients. The overall survival in patients with CC is clinically associated with lifestyle choices before CC diagnosis. A balanced diet, walking and other forms of exercise should be strongly recommended to the community and those undergoing screening colonoscopy.</p> Saira Saleem Iffat Aleem Muhammad Zeshan Muhammad Abu Bakar Aribah Atiq Muhammad Tahseen Mohammad Tariq Mahmood Sadia Hassan Aamir Ali Syed Mudassar Hussain Asad Hayat Ahmad Shahid Khattak Muhammed Aasim Yusuf Copyright (c) 2022 Iffat Aleem, Saira Saleem, Muhammad Zeshan, Muhammad Abu Bakar, Aribah Atiq, Muhammad Tahseen, Mohammad Tariq Mahmood, Sadia Hassan, Aamir Ali Syed, Mudassar Hussain, Asad Hayat Ahmad, Shahid Khattak, Muhammed Aasim Yusuf 2022-06-30 2022-06-30 8 2 10.37029/jcas.v8i2.477 Follicular Lymphoma of Breast: a Case Report from Pakistan <p><strong>Introduction:&nbsp;</strong>Breast Lymphoma (BL) is a rare breast tumor and accounts for less than 1% of all breast malignancies. It is further categorized into primary breast lymphoma and secondary breast lymphoma. This manuscript presents a case report of a patient diagnosed with secondary breast lymphoma.&nbsp;<strong>Case description:&nbsp;</strong>A<strong>&nbsp;</strong>51-year-old female presented in the one-stop breast clinic with six months history of having a static, painless left breast lump. Mass was firm, non-tender, and 2 cm in size. It was not adherent to skin or muscle, and it was present in the upper outer quadrant of the left breast. Mammo-sonography revealed a circumscribed mass of 17 mm in the outer quadrant of the left breast. There were enlarged ipsilateral lymph nodes. Core biopsy suggested atypical lymphoid infiltrates. She underwent wide local excision of breast and axillary nodal mass. The definitive histological diagnosis revealed a follicular lymphoma (FL) grade 2/3, non-Hodgkin's lymphoma. Staging computed tomography scan features were suggestive of cervical lymphadenopathy. Hence, staging workup proved this to be a case of secondary breast lymphoma.&nbsp;<strong>Practical implication:&nbsp;</strong>The early diagnosis of breast lymphoma is highly relevant. Its diagnosis is challenging due to non-specific clinical presentation and imaging features. Commonly FL is diagnosed on excisional biopsy or after wide local breast mass excision. Primary and secondary lymphomas, though rare, should be considered in the differential diagnosis of breast malignancies.</p> Namra Urooj Umair Ahmed Amina Khan Zulqarnain Chaudhry Muhammad Asad Parvaiz Copyright (c) 2022 Namra Urooj, Umair Ahmed, Amina Khan, Zulqarnain Chaudhry, Muhammad Asad Parvaiz 2022-06-02 2022-06-02 8 2 10.37029/jcas.v8i2.471