ON ENHANCING NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) ACTIVITY IN LIVING SYSTEMS

Abstract

Nicotinamide Adenine Dinucleotide (NAD) is a key molecule in intermediary metabolism and for the flow of energy in biological systems. It has been shown that a significant association exists in Drosophila melanogaster, the fruit fly, between larval development time, NAD and Adenosine Triphosphate (ATP)/Adenosine Diphosphate (ADP) ratio. Furthermore, variation in NAD concentration has been associated with both AIDS and Alzheimer's disease in humans. Recent studies have favorably implicated NAD as a medication fot patients suffering from both dementia of the Alzheimer type and HIV-l infection. In this paper, we have examined the possibility that both EMFs and intention-augmented EMFs significantly affect (1) the activity of NAD in solution over time and (2) the condition of the water used for preparing NAD solutions to be subsequently utilized for in vitro energy assays in D. melanogaster. Here, we show that NAD activity and the (ATP)/(ADP) ratio significantly depended on the treatments given to the water. Out results indicated (1) that a reduction in exposure to EMFs increased NAD activity and (2) that electronic devices that had been exposed to a human intention concerned with energy metabolism, positively influenced both the activity of NAD and the ATP/ADP ratio in vitro.