The Effects of a Static Magnetic Field on the sensitivity of Escherichia coli to Ampicillin, Streptomycin and Nalidixic Acid
Abstract
The goal of this study was to determine if we could increase the sensitivity of E. coli to antibiotics by exposing it to a static magnetic field (SMF). In this study, we exposed 12 mL aliquots of E. coil culture to a 19.5 mT SMF for 300-, 100-, 30-, or 10-minute intervals at 36 °C, then performed a disk diffusion assay using ampicillin, streptomycin and nalidixic acid. We looked for differences in the zones of inhibition (ZI) between SMF exposed and unexposed E. coli to quantify changes in antibiotic sensitivity. We found that exposure to SMF for 300 minutes results in a significantly larger ZI for ampicillin, and SMF exposure of 30-minutes reduced the ZI of streptomycin. Our results suggest that exposure to a 19.5 mT SMF can change E. coli’s susceptibility to ampicillin and streptomycin. This knowledge can be applied to developing an alternative treatment against infectious bacteria.
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