Risk Factors for Bladder Cancer: Results of a Survey of Hospital Patients

  • Rangrez Shadab Department of Urology, JN Medical College, and Urinary Biomarkers Research Centre, KLE Academy of Higher Education & Research, JNMC Campus, Belagavi
  • Rajendra Nerli Department of Urology, JN Medical College, and Urinary Biomarkers Research Centre, KLE Academy of Higher Education & Research, JNMC Campus, Belagavi
  • Saziya Bidi Department of Urology, JN Medical College, and Urinary Biomarkers Research Centre, KLE Academy of Higher Education & Research, JNMC Campus, Belagavi
  • Shridhar Ghagane Department of Biotechnology, Kaher's Dr. Prabhakar Kore Basic Science Research Center, V.K. Institute of Dental Science Campus, Belagavi, India
Keywords: Alcohol, bladder cancer, epidemiology, gender, genetics, occupation, risk factors, tobacco smoking

Abstract

Introduction: Several risk factors have been identified in the occurrence of bladder cancer. These include genetic and hereditary factors, smoking and tobacco use, increased body mass index, occupational exposure to certain chemicals and dyes, medical conditions such as chronic cystitis and infectious diseases such as schistosomiasis. This study aimed to evaluate risk factors in patients with bladder cancer. Materials and Methods: All patients presenting to the uro-oncology department of the hospital with imaging and histology confirmed bladder cancer were included in the study. Age- and gender-matched patients presenting to the department of urology with benign disorders were prospectively included as controls. All the study subjects and the controls completed a self-administered structured questionnaire. Results: Seventy-two (67.3%) of the participants with bladder cancer were males. The mean age of participants with bladder cancer was 59.24 ± 16.28 years. Most participants with bladder cancer worked as farmers (35.5%) or industrial workers (24.3%). Recent history of recurrent urinary tract infections was seen in 85 (79.4%) of the participants with bladder cancer and 32 (30.8%) of controls. Diabetes mellitus was more common among participants with bladder cancer. A significant number of participants with bladder cancer used tobacco and smoked compared to controls. Conclusions: This study highlights numerous potential biological and epidemiological factors that may act as a risk factors for bladder cancer. These factors could explain the gender differences observed in the incidence of bladder cancer. In addition, the study indicates the intense.

Published
2022-09-30
How to Cite
1.
Shadab R, Nerli R, Bidi S, Ghagane S. Risk Factors for Bladder Cancer: Results of a Survey of Hospital Patients. J Cancer Allied Spec [Internet]. 2022Sep.30 [cited 2023Feb.3];9(1). Available from: https://journals.sfu.ca/jcas/index.php/jcas/article/view/485
Section
Original Research Article